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ATCC
carcinoma a498 renal carcinoma achn renal adinocarcinoma caki Carcinoma A498 Renal Carcinoma Achn Renal Adinocarcinoma Caki, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/cell+lines+a498+atcc/us09017732-134-185-222?v=ATCC Average 96 stars, based on 1 article reviews
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JCRB Cell Bank
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Image Search Results
Journal: International journal of oncology
Article Title: Long non-coding RNA HOTTIP promotes renal cell carcinoma progression through the regulation of the miR-615/IGF-2 pathway.
doi: 10.3892/ijo.2018.4539
Figure Lengend Snippet: Figure 1. HOTTIP expression and its association with the clinical parameters in renal cancer tissues. (A) Expression of HOTTIP in RCC from our clinical specimens. (B) Results of RT-qPCR showing the expression levels of HOTTIP in RCC cell lines. (C) HOTTIP RNAseq expression data were retrieved from the TCGA database. The Wilcoxon signed-rank test was used for the comparison. (D) The overall survival (OS) and disease-free survival (DFS) curve for patients with RCC with low vs. high HOTTIP expression (Kaplan-Meier method). *P<0.05, **P<0.01. RCC, renal cell carcinoma.
Article Snippet: The
Techniques: Expressing, Quantitative RT-PCR, Comparison
Journal: Translational Andrology and Urology
Article Title: RhoJ promotes the progression of clear cell renal cell carcinoma via the TNF-α/NF-κB axis
doi: 10.21037/tau-2025-132
Figure Lengend Snippet: RhoJ knockdown inhibits the proliferation of ccRCC cells in vivo and in vitro . (A) CCK-8 assay assessing the viability of ccRCC cells. (B) Colony formation assay assessing the colony-forming ability of ccRCC cells (crystal violet staining). (C) EdU proliferation assay assessing the proliferation levels of ccRCC cells. (D) Tumor size of orthotopic xenograft models. (E,F) Cell cycle analysis of A498 (E) and 786-O (F) cells. (G) Apoptosis analysis of A498 and 786-O cells. *, P<0.05; **, P<0.01; ***, P<0.001; ****, P<0.0001; ns, not significant, P≥0.05. ccRCC, clear cell renal cell carcinoma; CCK-8, Cell Counting Kit-8; EdU, 5-ethynyl-2'-deoxyuridine; NC, negative control; RhoJ, Ras-homologous gene family member J.
Article Snippet:
Techniques: Knockdown, In Vivo, In Vitro, CCK-8 Assay, Colony Assay, Staining, Proliferation Assay, Cell Cycle Assay, Cell Counting, Negative Control
Journal: Translational Andrology and Urology
Article Title: RhoJ promotes the progression of clear cell renal cell carcinoma via the TNF-α/NF-κB axis
doi: 10.21037/tau-2025-132
Figure Lengend Snippet: RhoJ knockdown inhibits migration, invasion, and EMT in ccRCC cells. (A,B) Effect of RhoJ knockdown on ccRCC cell migration was assessed via wound healing assay. (A) The results were observed under an optical microscope and calculated within ImageJ. (B) Quantification of migration rate. (C,D) Effect of RhoJ knockdown on ccRCC cell migration and invasion was assessed via Transwell assay with crystal violet staining (scale bar, 20 µm; C), quantification of migration rate (D). (E) Correlation analysis between RhoJ and Bcl-2, SNAI1, VIM, and ZEB1 based on TCGA-KIRC database. (F) Western blot analyses of EMT and apoptosis-related markers in RhoJ knockdown and overexpression ccRCC cells. *, P<0.05; **, P<0.01; ***, P<0.001; ****, P<0.0001. ccRCC, clear cell renal cell carcinoma; EMT, epithelial-mesenchymal transition; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; NC, negative control; RhoJ, Ras-homologous gene family member J; SNAI1, snail family transcriptional repressor 1; TCGA-KIRC, The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma; TPM, transcript per million; VIM, Vimentin; ZEB1, zinc finger E-box binding homeobox 1.
Article Snippet:
Techniques: Knockdown, Migration, Wound Healing Assay, Microscopy, Transwell Assay, Staining, Western Blot, Over Expression, Negative Control, Binding Assay